Inclusion Criteria:

• - Age ≥ 18.

• - Confirmed diagnosis of Multiple Sclerosis based on McDonald criteria.

• - Minimal one month from last relapse.

• - Possibility to use smartphone or tablet because of using rehabilitation application.

Exclusion Criteria:

- Illnesses which can limiting exercises activities (e.g. orthopedic, cardiology or other neurological diseases) - Cognitive deficit which can limiting cooperation (fill a questionnaire, comply with movement task, using application) - Relapse of diseases during study

In the Czech population more than 20,000 people have been diagnosed with multiple sclerosis (MS), an autoimmune disease affecting a patient's central nervous system. This disease has a wide range of symptoms, with the most common ones being various motor disorders that negatively affect the locomotor function and patients' quality of life. The positive effect of physical activity on human health is well known. This study aims to examine the effect of hybrid exercise program on people with MS. This exercise program includes ambulatory circuit training for twelve weeks followed by telerehabilitation. The aim of the study is to find out whether the exercise program will positively affect the movement skills of probands and improve their quality of life. Testing will done before the start of the exercise program, after twelve weeks and after 6 months. Movement skills will be tested by a set of movement tests called miniBEST test. For measuring quality of life the investigators will the SF-36 questionnaire will be used. Another goal will analyze participants' satisfaction with the intervention and adherence to regular physical activity. The investigators anticipate that regular physical training combined with telerehabilitation will increase the motivation and effectiveness of independent training in people with MS leading to improvment of physical fitness, physical activity levels and quality of life.

Arms

Experimental: Circuit training and telerehabilitation

The experimental group will participate in a 12-week rehabilitation program, including training once a week. After the end of this outpatient program, participants will gain access to a mobile application in which participants will record all their physical activities.The mobile application will also include a library of exercises taught during the outpatient program so patients can practice them at home.

Sham Comparator: Usual Care

Patients have usual care and usual information about importance of regular movement activities and recommendation of proper exercises. Patients don't visit ambulatory rehabilitation program and they don't have access to an application

Interventions

Other: - Circuit training followed by telerehabilitation

Patients participate in an ambulatory rehabilitation program (12 weeks) and then gain access to mobile application to record their movement activities. This application will aslo inlude a library with exercise vidoes from the ambulatory program. These videos should inspire patients to do the exercises at home.

Other: - Usual care

Patients have usual information about importance of regular movement activities and recommendation of proper exercises