Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Impact of Neuropsychological Disorders in Multiple Sclerosis

Study Purpose

The study involves MS patients with and without neuropsychological disorders. The patient will benefit from:

- A routine neuropsychological assessment, including a cognitive and emotional assessment.

- A clinical examination.

- A three-dimensional analysis of movement

Recruitment Criteria

Accepts Healthy Volunteers Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms	No
Study Type An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes. An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes. Searching Both is inclusive of interventional and observational studies.	Interventional
Eligible Ages	18 Years - 55 Years
Gender	All

More Inclusion & Exclusion Criteria

Inclusion Criteria:

- Understanding and able to speak French.

- Carriers of MS with relapsing remitting form (RRMS-RR) with an EDSS <4.

- No significant motor, cerebellar or somesthesia disorders of the upper limbs or visual disturbances (side to a visual EDSS <2) - Absence of corticosteroid intake in the last four weeks.

- Benefiting from health insurance coverage.

- Not showing any flare-ups or worsening of the disease in the last 6 weeks.

- No botulinum toxin injection for more than 4 months.

Exclusion Criteria:

- People with previous neurological pathologies, head trauma with loss of consciousness, psychiatric pathologies, serious general ailments, perceptual or dysarthric disorders preventing verbal communication or reading, - Treatment with psychotropic drugs (except benzodiazepines and hypnotics).

- Refusal to participate after clear and fair information about the study.

- Adults under tutorship, curatorship or safeguard of justice.

- With orthopedic treatment influencing walking.

- Pregnant woman

Trial Details

Trial ID: This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries.	NCT04837365
Phase Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans. Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data. Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs. Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use.	N/A
Lead Sponsor The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data.	Lille Catholic University
Principal Investigator The person who is responsible for the scientific and technical direction of the entire clinical study.	Caroline Massot, MD
Principal Investigator Affiliation	GHICL
Agency Class Category of organization(s) involved as sponsor (and collaborator) supporting the trial.	Other
Overall Status	Recruiting
Countries	France
Conditions The disease, disorder, syndrome, illness, or injury that is being studied.	Multiple Sclerosis

Arms & Interventions

Arms

Other: patients with neuropsychological disorders

Other: patients without neuropsychological disorders

Interventions

Other: - Three dimensional gait analysis with eyetracking

An emotional impregnation and eye pursuit assessment are specific to the study. Emotional impregnation involves making the patient look at images from the International Affective Picture System (IAPS) on a screen before initiating walking. The equipment will be identical to that of the patient during walking tasks. Eye movement analysis is performed using a pair of eyetracking glasses.

Contact a Trial Team

If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.